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Erythromycin- Process Optimization

A listed company in Hubei produces erythromycin, but the product quality is unstable and the yield is low. GBC was commissioned by the company to improve the product quality and yield.

The technical team was sent to the enterprise to follow the production of the enterprise for two batches, to conduct comprehensive and systematic observation, research and demonstration on its existing process and method, to make adjustments on the concentration and time of fermentation replenishment, and to apply membrane filtration and crystallization process in the post-extraction, so that the yield reached more than 85%, the main component was obviously increased and impurities were reduced, achieving satisfactory results from both sides.


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